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GFBP Test kit

The Insulin-like growth factor binding protein 1 (iGFBP-1) rapid test (vaginal secretion) is a visually interpreted, qualitative immunochromatographic dipstick test for detection of iGFBP-1 in vaginal secretions during pregnancy, which is a major protein marker of the amniotic fluid in a vaginal sample. The test is intended for professional use to help diagnose the rupture of fetal membranes (ROM) in pregnant women.

 

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 Product NameFactory home use igfbp strip  test kits for women's healthcare igfbp-1 test cassette for self-testing
 Specimen Secretion
 Method Colloidal Gold immune chromatographic assay
 Form/ Dosage Form In Vitro Diagnostic Medical Rapid test Cassette
 Reading Time within 10-15 mins
 Accuracy about 99%
 Format Strip or Cassette
 Certification CE, ISO13485
 Shelf Time 24 months
 Package 20 tests/box


 

Insulin-like growth factor-binding protein 1 (i-GFBP-1) known as placental protein 12 (PP12) is a protein that in humans is encoded by the IGFBP1 gene. IGFBPs is believed to be important in the regulation of fetal and neonatal growth. We previously reported that the profiles of IGFBPs in fetal cord serum (FCS) were dependent on the growth/metabolic status of the fetus. It can be detected in cervical secretions of pregnant women with preterm uterine contractions, and whether their presence predicts an increased risk of preterm delivery. The abundance of insulin-1like growth factor binding protein-11 at the maternal-1fetal interface in severely preeclamptic pregnancies suggests that the binding protein may participate in the pathogenesis of the shallow placental invasion observed in this disorder. Low circulating insulin-like growth factor-1 and elevated insulin1like growth factor binding protein-1 levels may contribute to restricted placental and therefore fetal growth.

 

 

Intend to use

 The Insulin-like growth factor binding protein 1 (iGFBP-1) rapid test (vaginal secretion) is a visually interpreted, qualitative immunochromatographic dipstick test for detection of iGFBP-1 in vaginal secretions during pregnancy, which is a major protein marker of the amniotic fluid in a vaginal sample. The test is intended for professional use to help diagnose the rupture of fetal membranes (ROM) in pregnant women.


 

Operating  Steps

 

Allow the test device, specimen, buffer, and/or controls to equilibrate to room temperature (15-30°C) prior to testing.

1.   Remove the test device from the foil pouch and use it as soon as possible. Best resultswill be obtained if the assay is performed within one hour.

2.   Place the test device on a clean and level surface. Transfer the specimen by a pipette or a dropper:

  • To use a Pipette: Transfer 5 mL of whole blood to specimen well of the test device, and then add 3 drops of buffer (approximately 180ul), and start the timer.

  • To use a Disposable Specimen Dropper: Hold the dropper vertically; draw the specimen up to the Fill Line (approximately 5ul). Transfer the specimen to the specimen well, then add 3 drops of buffer (approximately 180ul) and start the timer.

  • Wait for the colored line(s) to appear. The result should be read at 10 minutes.  Do not interpret the result after 20 minutes.

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